First: Principles

Last time I had decided that to efficiently analyze the reads, we had to make an index of the human genome. So how do we go about that? ...

Last time I discussed using a program called BWA to try to determine if a given sequence was part of the human genome or not. It didn't...

Last time I discussed a million-dollar challenge posted by Innocenture . The challenge is to analyze a series of DNA reads and determine th...

Of course, you have to do a few things to earn it. Innocenture is running a challenge, with a million dollar prize, for the ability to take ...

A little story about immune responses in cells. Type-I interferons (IFNs) are important for antiviral and autoimmune responses.  They int...

This fall, for the first time, I've had the professional opportunity to work on some Python code. I find the language quite elegant and...

What the fossil record shows about Denisovans: They had at least one finger, one toe, and a tooth. View Larger Map This evidence comes...

The problem: A method for analysing similarities in protein sequences is to use a substitution scoring matrix. The matrix will assign a s...

Rosemary J. Redfield wrote an article on the teaching of genetics that resonated with me. Apparently the standard theory for teaching genet...

It seems some East Coast researchers are pushing the envelope in storing information in DNA. They encoded a book , roughly 5 megabits of da...

In the fall I'll be enrolling for classes once more. Cathy's now finished her Doctor of Nursing Practice degree so now it's my t...

The DevExpress ASPxScheduler control is a nice calendar control. It seems to take a fair amount of code and study to get all the bits of ...

For a while, Scott Rosenberg at Wordyard would send a free copy of his book to anyone who was willing to review it. Thanks, Scott! Here'...

Four years ago I took the plunge and started blogging. And today...well, I probably have just about the same number of readers as I did the...

SHHHHHHHHHHHHH. Please NO talking about the company to anyone. No blogging, talking, posting, emailing about the company’s particulars, etc…...

Wow, looks like the Bloomington Startup Weekend is proceeding apace. It was announced today as an official part of the Startup Weekends t...

I really don't care that much for Facebook . I don't watch enough movies to take the little quizzes, and I'm not really all that...

Jeff Atwood over at Coding Horror is asking for comments on the relative efficiency of these processes. We do both at my company, and while ...

So on my basketball fan page, HoosierBall , I was working on the schedule display. I had originally set up a simple widget from Zvents, but ...

More of my writeup on the XUnit session I went to nearly two months ago. I hope someday to make all of my note-taking blog entries coherent ...