First: Principles

At work I maintain a little Ruby on Rails site. Not a particularly interesting site, just a set of pages of statistics gathered from various...

In January a site went live called  readingroom.info . I suspect due to the timing and the subject matter it was a student project. The idea...

I wrote earlier about Fitnesse and Slim style integration testing. There are only a few commands associated with Slim tables, but the pre...

Fitnesse is a rather nice testing tool. It's been around since what seems like the beginning of the integration testing movement. It'...

In our quest to win a million dollars , we're trying to Index the Human Genome . A typical index, like in the back of a book, is compose...

Last time I had decided that to efficiently analyze the reads, we had to make an index of the human genome. So how do we go about that? ...

Last time I discussed using a program called BWA to try to determine if a given sequence was part of the human genome or not. It didn't...

Last time I discussed a million-dollar challenge posted by Innocenture . The challenge is to analyze a series of DNA reads and determine th...

Of course, you have to do a few things to earn it. Innocenture is running a challenge, with a million dollar prize, for the ability to take ...

A little story about immune responses in cells. Type-I interferons (IFNs) are important for antiviral and autoimmune responses.  They int...

This fall, for the first time, I've had the professional opportunity to work on some Python code. I find the language quite elegant and...

What the fossil record shows about Denisovans: They had at least one finger, one toe, and a tooth. View Larger Map This evidence comes...

The problem: A method for analysing similarities in protein sequences is to use a substitution scoring matrix. The matrix will assign a s...

Rosemary J. Redfield wrote an article on the teaching of genetics that resonated with me. Apparently the standard theory for teaching genet...

It seems some East Coast researchers are pushing the envelope in storing information in DNA. They encoded a book , roughly 5 megabits of da...

In the fall I'll be enrolling for classes once more. Cathy's now finished her Doctor of Nursing Practice degree so now it's my t...

The DevExpress ASPxScheduler control is a nice calendar control. It seems to take a fair amount of code and study to get all the bits of ...

For a while, Scott Rosenberg at Wordyard would send a free copy of his book to anyone who was willing to review it. Thanks, Scott! Here'...

Four years ago I took the plunge and started blogging. And today...well, I probably have just about the same number of readers as I did the...

SHHHHHHHHHHHHH. Please NO talking about the company to anyone. No blogging, talking, posting, emailing about the company’s particulars, etc…...